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TGM2, transglutaminase 2 Vertebrate Orthologs 9 Human Ortholog TGM2, transglutaminase 2 Orthology source: HomoloGene, HGNC Synonyms TGC, TG(C) Links HGNC:11778. NCBI Gene ID: 7052. neXtProt AC: NX_P21980. UniProt: P21980. Chr Location 20q11 Transglutaminase 2 expression was upregulated in the lungs of preterm infants with BPD and in the lungs of hyperoxia-exposed mouse pups, where lung development was arrested. Transglutaminase 2 localised to the developing alveolar septa.

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Transglutaminase 2 (TG2) has been reported to play a role in dendritic cell activation and B‐cell differentiation after immunization. Its presence and role in T cells, however, has not been explored. Transglutaminase 2 (TG2) is an inducible transamidating acyltransferase that catalyzes Ca 2+-dependent protein modifications.It acts as a G protein in transmembrane signalling and as a cell surface adhesion mediator, this distinguishes it from other members of the transglutaminase family. Transglutaminase 2 Synonym: Tissue-type Transglutaminase, TG2, TGase 2, TG C , tissue type protein-glutamine-γ-glutamyltransferase Factor XIII Transglutaminase 2 (TG2) is a multifunctional crosslinking enzyme that displays transamidation, protein disulfide isomerase, protein kinase, as well as GTPase and ATPase activities. TG2 can also act as an adhesion molecule involved in the syndecan and integrin receptor signaling. 2021-01-21 · Transglutaminase 2 (TG2), is a calcium-activated multifunctional enzyme, well known for the formation of ε-(γ-glutamyl)lysine isopeptide bonds that lead to protein cross-linking, that provide resistance to proteolytic cleavage and ultimately, stabilisation and increased stiffness of the ECM (Bergamini et al. 2011; Wang and Griffin 2012).

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2021-01-21 · Transglutaminase 2 (TG2), is a calcium-activated multifunctional enzyme, well known for the formation of ε-(γ-glutamyl)lysine isopeptide bonds that lead to protein cross-linking, that provide resistance to proteolytic cleavage and ultimately, stabilisation and increased stiffness of the ECM (Bergamini et al. 2011; Wang and Griffin 2012).

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2014-09-30 Tissue transglutaminase is the most specific test for Coeliac Disease. Gluten-sensitive patients react to Gliadin (found in wheat, barley and rye gluten) and to an antigenic component of the gut endomysium, now known to be tissue Transglutaminase (tTg), All lanes : Anti-Transglutaminase 2 antibody [CUB 7402] (ab2386) at 1 µg/ml Lane 1 : Wild-type A549 whole cell lysate Lane 2 : TGM2 knockout A549 whole cell lysate Lane 3 : HeLa whole cell lysate Lane 4 : Huvec whole cell lysate Lysates/proteins at 20 µg per lane.

TG2 can also act as an adhesion molecule involved in the syndecan and integrin receptor signaling. Transglutaminase 2 (TG2) is an inducible transamidating acyltransferase that catalyzes Ca 2+-dependent protein modifications.It acts as a G protein in transmembrane signalling and as a cell surface adhesion mediator, this distinguishes it from other members of the transglutaminase family. 2017-02-15 2021-01-21 2011-09-15 TGM2 (Transglutaminase 2) is a Protein Coding gene. Diseases associated with TGM2 include Dermatitis Herpetiformis and Balanitis Xerotica Obliterans. Among its related pathways are Ca, cAMP and Lipid Signaling and CREB Pathway. Transglutaminase 2 (TG2) is a multi- domain, multi-functional enzyme that post-translationally modifies proteins by catalyzing the formation of inter- molecular isopeptide bonds between glutamine and lysine side-chains.
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13.15-13.35. Ying Zhao, Stockholm. Core-shell structured gold nanoparticles for. (TG2). Vi har med dessa forskare (studie 3)kunnat påvisa antikroppar mot TG6 IgG och IgA mot gliadin(AGA)och transglutaminase 2(TG2)har  2.

Application His6-rhTG2 catalyzes acyl transfer reactions from glutamin residues in proteins or peptides to primary amines, e.
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One protein is an enzyme called tissue transglutaminase, or TTG, that is found in many cells of our body. TTG is released from the damaged intestine during active celiac disease, and antibodies to TTG are found to be elevated in the blood of most patients with untreated celiac disease. Transglutaminase, or meat glue, is a food additive used to improve the texture and appearance of foods like processed meats. Though major food safety organizations consider it safe, some health Tranglutaminase-2 (also known as TGM2, TG2), is a widely expressed, multifunctional protein. Application Anti-Transglutaminase-2 (C-terminal) antibody produced in rabbit has been used in: • immunoblotting • immunoprecipitation • immunofluorescence • immunohistochemistry.

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2006-09-01 · Transglutaminase 2 in inflammation. Kim SY(1). Author information: (1)Division of Basic Science, Research Institute, National Cancer Center, Goyang, Republic of Korea. kimsooyoul@gmail.com Many reports have shown that the expression of transglutaminase 2 (TG 2) is increased in inflammatory diseases. Tranglutaminase-2 (also known as TGM2, TG2), is a widely expressed, multifunctional protein. Application. Anti-Transglutaminase-2 (C-terminal) antibody produced in rabbit has been used in:• immunoblotting.

Transglutaminase 2 localised to the developing alveolar septa. TGF-b was identified as a regulator of transglutaminase 2 expression in human and mouse lung epithelial cells.